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Symbol
Name
ID
Akt1
thymoma viral proto-oncogene 1
MGI:87986
Phenotype annotations related to liver/biliary system
Darker colors indicate more annotations
Human Phenotypes
Hepatosplenomegaly
Extrahepatic cholestasis
Jaundice
Neoplasm of the liver
Disease(s) Associated with AKT1
pancreatic cancer

Mouse Phenotypes
biliary cyst
dilated bile duct
decreased liver triglyceride level
decreased hepatocyte number
decreased susceptibility to diet-induced hepatic steatosis
Availability Mouse Genotype
Akt1tm1Mbb/Akt1tm1Mbb
Akt1tm2.1Mbb/Akt1tm2.1Mbb
Akt1tm1.1Mjl/Akt1+
Akt1tm1Mjl/Akt1+
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sortm1(cre/ERT)Nat  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory